This comprehensive owner's manual provides a detailed guide for Mercedes-Benz S-Class models, including the S430, S500, S600, and S55 AMG, produced from 2000 to 2006. It covers all aspects of vehicle operation, maintenance, and care, ensuring a complete understanding of your S-Class sedan. The manual features clear instructions, detailed diagrams, and informative explanations to guide you through everything from basic controls and features to advanced systems and troubleshooting. It includes sections on interior and exterior features, engine operation, transmission, brakes, suspension, electrical systems, safety systems, and more. This manual is an essential resource for any owner of a Mercedes-Benz S-Class during this period, providing the knowledge and information needed to keep your vehicle running smoothly and safely.

The Mercedes-Benz S-Class, a symbol of luxury and engineering prowess, entered its W220 generation in the year 2000, bringing a refined and technologically advanced iteration to the flagship sedan segment. The S430, S500, and S600 models, powered by robust V8 and V12 engines, respectively, delivered exceptional performance and a serene driving experience. The S55 AMG, a performance-oriented variant, pushed the boundaries with its supercharged V8 engine, capable of exhilarating acceleration and handling. These sedans embodied the Mercedes-Benz philosophy of combining opulence with cutting-edge technology, showcasing features like innovative suspension systems, advanced safety features like Electronic Stability Program (ESP), and a plush interior boasting leather upholstery, wood trim, and high-end audio systems. Beyond the potent powertrains and opulent amenities, the W220 S-Class showcased a significant leap in technology. It introduced the groundbreaking Active Body Control (ABC) system, revolutionizing handling and ride comfort through hydraulically controlled suspension. The S-Class also pioneered the use of COMAND, a multi-function control system that integrated climate control, audio, navigation, and phone functionality into a single intuitive interface. This commitment to innovation ensured that the W220 S-Class remained at the pinnacle of luxury and technology, setting a benchmark for future generations of the iconic sedan. The S-Class, in its W220 form, cemented its reputation as a coveted symbol of status and sophistication, earning a place in automotive history as a transformative force in the luxury segment.